Studies have implicated Lamins in human disease for years. First in cancer, then in muscular dystrophy and cardiomyopathy, then ten years ago, in 2003 in premature ageing. Most recently, last year, Lamins have been implicated in normal ageing and Nuclear Antibodies against Lamins are now consid...
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Clustered regularly interspaced short palindromic repeat (CRISPR) and associated CRISP-R associated nuclease (Cas) proteins comprise the CRISPR/Cas systems responsible for adaptive immunity in many bacteria and archaea. Three types of CRISPR/Cas systems have been identified to date, designated t...
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Muslimov et al.
Abstract
In neurons, regulation of gene expression occurs in part through translational control at the synapse. A fundamental requirement for such local control is the targeted delivery of select neuronal mRNAs and regulatory RNAs to distal dendritic sites. The nature of spatial...
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