DNA Damage Recognition Antibodies

DNA damage recognition antibodies are useful in understanding mechanisms related to DNA repair, sets of linked processes in which a cell interprets and actively trys to correct damage to the DNA molecules that encode the cell genome.

DNA damage recognition antibodies research help elucidate damage caused by stressors, environmental (eg UV light, radiation ) and metabolic (e.g. oxidative and alkylation) and a cells ability to repair in the face of what can be up to 1 million molecular cell lesions per day.

DNA damage is implicated in wide range of disease areas including cancer and tumour formation.

DNA damage recognition antibodies are available in the following volumes 0.05 ml, 0.1 ml, 0.2 ml, 0.5 ml, 1ml and 2 ml

Histone H3 Monoclonal Antibody [1B1-B2] - ChIP Grade

Product Code:IQ606
Reactivity: Mouse, Human, Yeast
Application: WB, ChIP, IP, ICC/IF
Citation Count: 4
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ChIP - Histone H3 Antibody [1B1-B2]

Histone H3 (tri methyl K9) Monoclonal Antibody [6F12-H4]

Product Code:IQ549
Reactivity: Reacts with Human and cow. predicted to detect many other species due to sequence identity such as Mouse, Rat, Rabbit, Hamster, Pig, Saccharomyces cerevisiae, Fruit fly (Drosophila melanogaster), Non Human Primates
Application: Dot blot, ELISA, WB, ChIP, IHC-Fr, ICC/IF
Citation Count: 17
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Immunofluorescence analysis of paraformaldehyde fixed HeLa cells,  permeabilized with 0.15% Triton. Primary incubation 1hr (1:100 dilution) followed by Alexa Fluor® 488 secondary antibody (1:1000 dilution), showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Mouse IgG1 negative control followed by Alexa Fluor® 488 secondary antibody.

RNA polymerase II CTD repeat YSPTSPS (phospho S5) Monoclonal Antibody [8A7]

Product Code:IQ586
Reactivity: Human, Saccharomyces cerevisiae.Predicted to work with: Mouse, Hamster, Arabidopsis thaliana, Fruit fly (Drosophila melanogaster), Schizosaccharomyces pombe
Application: Flow Cyt, ICC/IF, ELISA, WB
Citation Count: 9
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RNA polymerase II CTD repeat YSPTSPS (phospho S5) Monoclonal Antibody [8A7]

ORC1 Monoclonal Antibody [7A7]

Product Code:IQ309
Reactivity: Human
Application: IP, WB
Citation Count: 1
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Nuclear extracts were prepared of Raji or Hela cells as shown, and immunoprecipitation was performed with ORC complex specific antibodies followed by Western blotting.  ORC proteins are  immunoprecipitated as a complex, and individual proteins can then be identified by WB

ORC3L Monoclonal Antibody [1D6]

Product Code:IQ308
Reactivity: Human
Application: IP, WB
Citation Count: 1
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Nuclear extracts were prepared of Raji or Hela cells as shown, and immunoprecipitation was performed with ORC complex specific antibodies followed by Western blotting.  ORC proteins are  immunoprecipitated as a complex, and individual proteins can then be identified by WB

ORC2 Monoclonal Antibody [3G6]

Product Code:IQ307
Reactivity: Human
Application: WB, IP
Citation Count: 3
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Nuclear extracts were prepared of Raji or Hela cells as shown, and immunoprecipitation was performed with ORC complex specific antibodies followed by Western blotting.  ORC proteins are  immunoprecipitated as a complex, and individual proteins can then be identified by WB

ORC6L Monoclonal Antibody [3A4]

Product Code:IQ306
Reactivity: Human
Application: IP, WB, ChIP
Citation Count: 2
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Immunoprecipitation using ORC6L Antibody (IQ306) on Raji and HelaS3 cells