Nuclear envelope antibodies relate to the nuclear envelope which is a thin membrane that surrounds the genetic material in eukaryotic cells. It consists of a double layer of lipids, separating the nucleus content, principally DNA, from the surrounding cell cytoplasm.
The outer part of the nuclear envelope membrane is rough endoplasmic reticulum spotted as it is with ribosomes. The inner part consists of flat membrane proteins e.g. Emerin which are linked to the nuclear lamina and mutations in Lamins A and B
These mutations are thought to be linked to laminopathic diseases like Emery Dreifuss muscular dystrophy, limb-girdle muscular dystrophy type 1B, dilated cardiomyopathy with conduction defect, and Charcot-Marie-Tooth disorder type 2B1 which the use of nuclear envelope antibodies reach is indicated
The nuclear envelope is perforated with pores which enable the transport of proteins and RNA between the nucleus and cytoplasm. The inner and outer membrane conjoin at each nuclear pore site.
Nuclear envelope antibodies are available in various quantities including 0.05 ml, 0.1ml, 0.2 ml ,1 ml.
SUN2 Antibody
Product Code: | IQ444 |
Reactivity: | Mouse |
Application: | Immunoblot, Immunofluorescence |
Citation Count: | 1 |
Lamin A/C antibody [JOL3]: FITC
Product Code: | IQ656FITC |
Reactivity: | Human, Mouse, Rat |
Application: | Immunofluorescence,Immunocytochemistry |
Citation Count: | 1 |
Lamin A+C Antibody [JOL2]: Horseradish peroxidase
Product Code: | IQ608HRP |
Reactivity: | Human, African Green Monkey |
Application: | Immunoblot,Immunohistochemistry (paraffin sections),Western blot,Immunoprecipitation |
Citation Count: | 1 |
Lamin A+C Antibody [JOL2]
Product Code: | IQ608 |
Reactivity: | Human, African Green Monkey |
Application: | Immunoblot,Immunohistochemistry (paraffin sections),Western blot,Immunoprecipitation |
Citation Count: | 4 |
Nesprin 2 Antibody [K20-478-5]
Product Code: | IQ562 |
Reactivity: | Human |
Application: | Immunoblot,Immunocytochemistry,Immunoprecipitation |
Citation Count: | 3 |
SUN2 Antibody
Product Code: | IQ563 |
Reactivity: | Human |
Application: | Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation |
Nesprin 2 Antibody
Product Code: | IQ565 |
Reactivity: | Mouse |
Application: | Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation |
Nesprin 3 Antibody
Product Code: | IQ566 |
Reactivity: | Mouse |
Application: | Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation |
Lamin A+C mutant R453W Antibody [12A-2F5]
Product Code: | IQ541 |
Reactivity: | Human |
Citation Count: | 1 |
Lamin A+C Antibody [JOL2]
Product Code: | IQ332 |
Reactivity: | Human, African Green Monkey |
Application: | Immunohistochemistry (paraffin sections),Western blot,Flow cytometry,Immunoprecipitation |
Citation Count: | 38 |
Lamin A Antibody [JOL4]
Product Code: | IQ330 |
Reactivity: | Human, Mouse |
Application: | Immunofluorescence, Immunohistochemistry (frozen sections), Western blot, Immunoprecipitation |
Emerin Antibody
Product Code: | IQ324 |
Reactivity: | Mouse, Rat, Hamster |
Application: | Immunoblot,Immunofluorescence |
Emerin Antibody
Product Code: | IQ323 |
Reactivity: | Mouse, Rat, Hamster, Human |
Application: | Immunoblot,Immunofluorescence |
Citation Count: | 1 |
TAP1 Antibody [53H8]
Product Code: | IQ279 |
Reactivity: | Human |
Application: | ELISA,Immunofluorescence,Western blot,Immunoprecipitation |
Lamin A + C antibody [JoL5] - Nuclear Envelope Marker
Product Code: | IQ252 |
Reactivity: | Mouse, Human |
Application: | Immunofluorescence, Western blot |
Citation Count: | 1 |
Lamin A+C Antibody [JoL3] - Nuclear Envelope Marker
Product Code: | IQ251 |
Reactivity: | Mouse, Rat, Human |
Application: | Immunofluorescence, Western blot |
Citation Count: | 2 |
Lamin A + C antibody [JoL5] - Nuclear Envelope Marker
Product Code: | IQ188 |
Reactivity: | Mouse, Human |
Application: | Immunofluorescence,Western blot |
Citation Count: | 3 |
Lamin C Antibody
Product Code: | IQ177 |
Reactivity: | Human, Mouse, Rat |
Application: | Immunoblot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunohistochemistry (paraffin sections), Flow cytometry |
Citation Count: | 5 |
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