Nuclear Envelope Antibodies

Nuclear envelope antibodies relate to the nuclear envelope which is a thin membrane that surrounds the genetic material in eukaryotic cells. It consists of a double layer of lipids, separating the nucleus content, principally DNA, from the surrounding cell cytoplasm.

The outer part of the nuclear envelope membrane is rough endoplasmic reticulum spotted as it is with ribosomes. The inner part consists of flat membrane proteins e.g. Emerin which are linked to the nuclear lamina and mutations in Lamins A and B

These mutations are thought to be linked to laminopathic diseases like Emery Dreifuss muscular dystrophy, limb-girdle muscular dystrophy type 1B, dilated cardiomyopathy with conduction defect, and Charcot-Marie-Tooth disorder type 2B1 which the use of nuclear envelope antibodies reach is indicated

The nuclear envelope is perforated with pores which enable the transport of proteins and RNA between the nucleus and cytoplasm. The inner and outer membrane conjoin at each nuclear pore site.

Nuclear envelope antibodies are available in various quantities including 0.05 ml, 0.1ml, 0.2 ml ,1 ml.

SUN2 Antibody

Product Code:IQ444
Reactivity: Mouse 
Application: Immunoblot, Immunofluorescence
Citation Count: 1
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Lamin A/C antibody [JOL3]: FITC

Product Code:IQ656FITC
Reactivity: Human, Mouse, Rat
Application: Immunofluorescence,Immunocytochemistry
Citation Count: 1
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Lamin A+C Antibody [JOL2]: Horseradish peroxidase

Product Code:IQ608HRP
Reactivity: Human, African Green Monkey
Application: Immunoblot,Immunohistochemistry (paraffin sections),Western blot,Immunoprecipitation
Citation Count: 1
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Lamin A+C Antibody [JOL2]

Product Code:IQ608
Reactivity: Human, African Green Monkey
Application: Immunoblot,Immunohistochemistry (paraffin sections),Western blot,Immunoprecipitation
Citation Count: 4
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Nesprin 2 Antibody [K20-478-5]

Product Code:IQ562
Reactivity: Human 
Application: Immunoblot,Immunocytochemistry,Immunoprecipitation
Citation Count: 3
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SUN2 Antibody

Product Code:IQ563
Reactivity: Human 
Application: Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation
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Nesprin 2 Antibody

Product Code:IQ565
Reactivity: Mouse 
Application: Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation
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Nesprin 3 Antibody

Product Code:IQ566
Reactivity: Mouse 
Application: Immunoblot, Immunofluorescence, Western blot, Immunoprecipitation
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Lamin A+C mutant R453W Antibody [12A-2F5]

Product Code:IQ541
Reactivity: Human
Citation Count: 1
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Lamin A+C Antibody [JOL2]

Product Code:IQ332
Reactivity: Human, African Green Monkey
Application: Immunohistochemistry (paraffin sections),Western blot,Flow cytometry,Immunoprecipitation
Citation Count: 38
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Lamin A Antibody [JOL4]

Product Code:IQ330
Reactivity: Human, Mouse
Application: Immunofluorescence, Immunohistochemistry (frozen sections), Western blot, Immunoprecipitation
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Emerin Antibody

Product Code:IQ324
Reactivity: Mouse, Rat, Hamster
Application: Immunoblot,Immunofluorescence
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Emerin Antibody

Product Code:IQ323
Reactivity: Mouse, Rat, Hamster, Human
Application: Immunoblot,Immunofluorescence
Citation Count: 1
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TAP1 Antibody [53H8]

Product Code:IQ279
Reactivity: Human 
Application: ELISA,Immunofluorescence,Western blot,Immunoprecipitation
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Lamin A + C antibody [JoL5] - Nuclear Envelope Marker

Product Code:IQ252
Reactivity: Mouse, Human
Application: Immunofluorescence, Western blot
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Lamin A+C Antibody [JoL3] - Nuclear Envelope Marker

Product Code:IQ251
Reactivity: Mouse, Rat, Human
Application: Immunofluorescence, Western blot
Citation Count: 2
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Lamin A + C antibody [JoL5] - Nuclear Envelope Marker

Product Code:IQ188
Reactivity: Mouse, Human
Application: Immunofluorescence,Western blot
Citation Count: 2
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Lamin C Antibody

Product Code:IQ177
Reactivity: Human, Mouse, Rat 
Application: Immunoblot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunohistochemistry (paraffin sections), Flow cytometry
Citation Count: 5
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