Checkpoint Control Antibodies

Checkpoint control antibodies that helps to understand the regulatory pathways of the cell cycle via a series of checkpoints which are coterminous with each part of the well established cell cycle mechanisms.

Check point control antibodies are utilized in research in understanding the cell phasing pathways and the prevention of DNA damage across the cell cycle.

Checkpoint control antibodies are implicated in genetic instability birth defects and cancer biology.

Checkpoint control antibodies are available in the following volumes including 0.05 ml, 0.1ml, 0.2 ml, 1 ml and 2 ml.

Mad1 Monoclonal Antibody [9B10]

Product Code:IQ200
Reactivity: Human
Application: IP, ICC/IF, Flow Cyt
Citation Count: 2
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HeLa lysate run on 4-12% Bis-Tris 2D gel in 1 x MOPS running buffer. Transfer to 0.45µm nitrocellulose. Membrane probed with P22.9B10.F6 (anti-MAD1L1). Anti-mouse IgG (whole molecule)-AP conjugate (1 in 2,000). Detection with BCIP/NBT substrate.

Mad2 Antibody

Product Code:IQ243
Reactivity: Human, Saccharomyces cerevisiae
Application: WB, ICC/IF
Citation Count: 2
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Western blot using Mad2p Antibody (IQ243) and yeast extracts

Mad1 Antibody

Product Code:IQ242
Reactivity: Saccharomyces cerevisiae
Application: WB, ICC/IF
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Western blot using Mad1p Antibody (IQ242) and yeast extracts

Mad2L1 Monoclonal Antibody [17D10]

Product Code:IQ239
Reactivity: Human
Application: IHC(P), IP, WB
Citation Count: 8
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Immunohistochemistry staining of the Mad2L1 antigen in colon cancer using IQ239 antibody.  Tissues were formalin-fixed and paraffin-embedded. Antibody was used at 1/200 dilution for 1hour at room temperature  following antigen retrieval with Tris-EDTA pH9

CENPE Monoclonal Antibody [1H12]

Product Code:IQ201
Reactivity: Human 
Application: ICC/IF, IP, ICC, Flow Cyt
Citation Count: 19
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Immunofluorescence -  Anti-CENPE Antibody (1H12) on Ovarian cancer cells

Bub1 Monoclonal Antibody [14H5]

Product Code:IQ198
Reactivity: Mouse, Human. Predicted to work with: Rat, Xenopus laevis, Kangaroo
Application: Flow Cyt, ICC/IF, WB, IHC-P
Citation Count: 4
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IF using Bub1 Antibody (IQ198) on Hela cells - shows kinetochore signal during early stages of mitosis but not in anaphase