Hormone & Receptor Antibodies

Hormone receptor antibodies are important in understanding how intar or surface cell receptor proteins binds to specific hormones.

These molecules are transcription factors that regulate gene expression in response to a wide range of developmental, physiological and environmental triggers.

Hormone and receptor antibodies are key products for drug discovery science as many are implicated in diabetes and other endocrine disorders as well as cancer.

Hormone and receptor antibodies are available in the following volumes including 0.05ml, 0.1ml, 0.2 ml, 1 ml and 2 ml.

Research Notes on Hormone and Receptor antibodies area available

Progesterone 11 alpha Antibody [45/23]

Progesterone is a steroid hormone secreted by the corpus luteum of the ovary and by the placenta, that acts to prepare the uterus for implantation of the fertilized ovum, to maintain pregnancy, and to promote development of the mammary glands

Product Code:IQ402
Reactivity: Human
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Parathyroid Hormone N-terminal Antibody [BAM1916]

PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Product Code:IQ398
Reactivity: Human
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Testosterone Antibody [FB83]

Testosterone is the principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually from cholesterol. Testosterone is necessary in the fetus for the development of male external genitalia. Testosterone also stimulates protein synthesis and accounts for the greater muscular development of the male. For many years, synthetic steroids similar to testosterone have been used by athletes with the goal of improving performance, although recent medical research has shown that these drugs may have a wide range of harmful side effects

Product Code:IQ396
Reactivity: Human
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Testosterone Antibody [R58]

Testosterone is the principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually from cholesterol. Testosterone is necessary in the fetus for the development of male external genitalia. Testosterone also stimulates protein synthesis and accounts for the greater muscular development of the male. For many years, synthetic steroids similar to testosterone have been used by athletes with the goal of improving performance, although recent medical research has shown that these drugs may have a wide range of harmful side effects

Product Code:IQ395
Reactivity: Human 
Application: ELISA
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ACTH N-Terminal Antibody 6Y8 [57]

FFPE of Human pituitary gland using Anti-ACTH N-Terminal, clone 6Y8

Product Code:IQ427
Reactivity: Human
Application: ELISA, Immunohistochemistry (paraffin sections)
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Parathyroid Hormone Antibody [BAM87]

IHC using Parathyroid Hormone Antibody [BAM87] on human FFPE parathyroid glandular tissue.

Product Code:IQ399
Reactivity: Human 
Application: ELISA, Immunohistochemistry (paraffin sections)
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Parathyroid Hormone Receptor 1 Antibody [3D1.1]

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone

Product Code:IQ393
Reactivity: Human
Application: ELISA, Immunoblot, Immunohistochemistry (paraffin sections), Western blot, Flow cytometry
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Progesterone Receptor Antibody (Phospho S162) [1064/E2]

Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap

Product Code:IQ345
Reactivity: Mouse, Human
Application: Western blot, Immunoprecipitation
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